2 Deoxy Ribose Purchase|Bulk 2-Deoxy-D-Ribose Powder

2-Deoxy-D-Ribose(2DDR)

2-Deoxy-D-Ribose (CAS 533-67-5) is a pentose derivative and fundamental component of the DNA backbone structure. GEM supplies 98% HPLC powder for pharmaceutical intermediates, nucleoside API synthesis, and research applications — distinct from D-Ribose used in sports nutrition.

As a specialized DNA sugar ingredient, 2-Deoxy-D-Ribose occupies a precise niche in the life-science supply chain. GEM offers this deoxy ribose powder to pharmaceutical manufacturers, contract research organizations, and nucleoside producers that require a consistent, high-purity carbohydrate building block. Every batch is supplied against a defined specification with full documentation, supporting customers from early-stage research through commercial API production.

Because 2-Deoxy-D-Ribose is chemically distinct from the better-known D-Ribose, sourcing the correct isomer matters. The two sugars share a five-carbon skeleton but differ at the 2-position, a structural difference that determines their entirely separate applications. The sections below explain the chemistry, specifications, and B2B supply details in full.

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Molecular Formula: C₅H₁₀O₄

Molecular Weight: 134.13

Certificate: ISO45001; ISO22000; ISO14001; ISO9001; BRC; Kosher; Halal

Annual Production Capacity: 50+ tons

Features: Fundamental DNA component; Pharmaceutical-grade supply.

Solubility: Freely soluble in water; Clear solution

Packing: 25 kg/drum

Lead Time: 3-5days if no storage.

Shelf Life: 12 months

MOQ: 1KG

Storage Conditions: Store in closed containers in a cool, dry area away from direct light.

Last updated: June 21, 2026

Quality Specification

Remark: Contact GEM team to request more info including COA, MSDS, Flow chart and price.

What Is 2 Deoxy D Ribose?

2-Deoxy-D-Ribose is an organic pentose sugar derivative that plays a crucial role in molecular biology and cellular biochemistry. Unlike standard D-Ribose, which contains a hydroxyl group ($-\text{OH}$) at the 2-position of the furanose ring, 2-Deoxy-D-Ribose Sugar lacks one oxygen atom at that position, giving rise to its "deoxy" designation.

In its solid crystalline state, Deoxy Ribose predominantly exists as a cyclic five-membered ring hemiacetal (furanose form) in dynamic equilibrium between its $\alpha$- and $\beta$-anomers.

GEM's 2DDR Advantage.

1: ISO, BRC, Kosher, Halal certified!

ISO9001 (quality management) ISO22000 (food safety management) ISO14001 (environmental management) BRC (a globally recognized food safety standard)

2: Stable Production Capacity.

Production capacity exceeds 50 tons per year, allowing GEM to serve both recurring R&D demand and large commercial intermediate orders from a single source.

3: Full Documentation and Batch Control

Every B2B order can be supported by a Specification Sheet, Certificate of Analysis (COA), and Material Safety Data Sheet (MSDS) to make order recorded with testing data and traceable.

4: Low Minimum Order Quantity

MOQ can be 1kg for your easy 2 deoxy ribose purchase whether it's for testing or trial order.

5: Flexible Payment Terms and Transportation Methods.

We accept payment like TT transfer, L/C, D/P, D/A, etc. We can delivery goods to you under terms such as FOB, CIF, CIP, DAP, DDP, or express like DHL, Fedex, TNT, etc. Make sure your 2 deoxy d ribose buy much more conveniently!

Application Fields

Pharmaceutical Intermediates

Beyond individual nucleosides, 2-Deoxy-D-Ribose 2DDR powder contributes to the production of deoxyribonucleotides and nucleoside analogs — compounds engineered to interrupt the replication of pathogens or the proliferation of abnormal cells.

Research & Development

Academic labs, biotech companies, and contract research organizations use 2-Deoxy-D-Ribose as a reagent in molecular biology and nucleic acid research. Whether constructing modified oligonucleotides or studying sugar chemistry, researchers benefit from a catalog-grade material with full documentation and a stable supply.

Potenial 2 Deoxy D Ribose Uses

Promotion of Angiogenesis and Tissue Repair
Recent preclinical studies suggest that 2-Deoxy-D-ribose (2dDR) can stimulate endothelial cell proliferation and angiogenesis. In animal models, it has demonstrated potential to accelerate wound healing and promote hair growth in areas affected by androgenetic alopecia. These effects are thought to be associated with activation of the HIF-1α/VEGF signaling pathway, although the underlying mechanisms remain under investigation. For information about 2 deoxy d ribose hair regrowth, please visit: ------------

Frequently Asked Questions

1. Can I buy 2-deoxy-d-ribose personally?

No, ours are raw ingredients, we just supply it to B2B business.

2. What quality standards does GEM 2-Deoxy-D-Ribose meet?

Assay 98% HPLC meeting with US and EU customers' request including ETO, Heavy metal, pesticides residue.

3. How should 2-Deoxy-D-Ribose be stored?

Store in a cool, dry place away from direct sunlight. Keep containers sealed. Shelf life is 12 months under recommended conditions.

4. Is 2-Deoxy-D-Ribose suitable for dietary supplements?

2-Deoxy-D-Ribose is primarily supplied as a pharmaceutical intermediate and research material. It is not positioned as a direct dietary supplement ingredient like D-Ribose. Confirm regulatory status in your target market before use.

5. What does "deoxy" mean in 2-Deoxy-D-Ribose?

"Deoxy" indicates that the molecule has one fewer oxygen atom than ribose — specifically, the hydroxyl group at the 2-position of ribose is replaced by a hydrogen. This missing 2'-oxygen is what distinguishes DNA (deoxyribonucleic acid) from RNA and defines the sugar's chemistry.

Pentose Sugar Classification

A pentose is a monosaccharide that contains five carbon atoms. Two families matter in biochemistry: aldopentoses, which carry an aldehyde group, and ketopentoses, which carry a ketone group. 2-Deoxy-D-Ribose is an aldopentose — its open-chain form presents an aldehyde at carbon 1. In solution and in the solid state, it cyclizes to a furanose ring, the same five-membered ring topology found in the deoxyribonucleosides of DNA.

The "D" in the name describes the absolute stereochemistry at the highest-numbered chiral center, placing the molecule in the D-series of sugars. Only the D-enantiomer occurs naturally in DNA, which is why commercial DNA sugar ingredient supply focuses exclusively on the D-form rather than a racemic mixture.

Why "Deoxy" Matters

The prefix "deoxy" signals the absence of one oxygen atom relative to ribose. At carbon 2 of the furanose ring, ribose bears a hydroxyl group; 2-Deoxy-D-Ribose replaces that hydroxyl with a hydrogen. This single-atom change removes the 2'-hydroxyl of the sugar, and that missing hydroxyl is precisely what distinguishes DNA from RNA at the molecular level. RNA retains the 2'-OH, while DNA does not — a structural fact that influences nucleic acid stability, enzymatic processing, and the chemical routes used to manufacture nucleoside analogs.

Source & Chemistry

2-Deoxy-D-Ribose is a naturally occurring sugar found in every cell that stores genetic information as DNA. In living systems the free sugar is rarely present in large quantities; instead, the deoxyribose moiety is built directly into deoxyribonucleotides. Cells generate these building blocks by reducing the corresponding ribonucleotides — a reaction catalyzed by the enzyme ribonucleotide reductase — so the deoxyribose unit is assembled as part of the nucleotide rather than added afterward.

For pharmaceutical and research supply, free 2-Deoxy-D-Ribose is produced through controlled synthetic or enzymatic routes that deliver the defined purity profile demanded by API manufacturers. GEM supplies the material to a 98% HPLC specification, ensuring that the deoxy ribose powder delivered to customers meets consistent stereochemical and purity standards batch after batch.

Relationship to Nucleosides and Nucleotides

Understanding the chemistry helps explain why 2-Deoxy-D-Ribose is valued as a pharmaceutical intermediate. A nucleoside pairs a nitrogenous base with a sugar; with deoxyribose, the result is a deoxyribonucleoside such as deoxyadenosine, deoxyguanosine, deoxycytidine, or thymidine. Add one or more phosphate groups and the molecule becomes a deoxyribonucleotide — the direct monomer of DNA.

Anomeric Forms and Purity

In the solid state, 2-Deoxy-D-Ribose crystallizes as a mixture of α- and β-anomers of the furanose ring. The ratio of these anomers, together with the optical rotation, confirms the identity and stereochemical integrity of the material. GEM's specification therefore includes a specific rotation range, an analytical parameter that distinguishes genuine 2-Deoxy-D-Ribose from related or incorrectly configured sugars.